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My Research

Here is a curated list of my research projects that includes genomics, epigenomics, computational toxicology and neurobiology:

1.  Ramesh V, Liu F, Minto MS, Chan U, West AE. Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics. Elife. 2023 Apr 24;12:e86273. doi: 10.7554/eLife.86273. 

 

2. Adams JI, Ferebee T, Minto MS, Pennerman KK, Chambwe N. Ten simple rules for creating a global network in computational biology. PLoS Comput Biol. 2022 Oct 27;18(10):e1010528. doi: 10.1371/journal.pcbi.1010528. 

3. Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G, McMullen PD, Andersen ME, Clewell Iii HJ. Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods. Front Pharmacol. 2022 Oct 7;13:980747. doi: 10.3389/fphar.2022.980747. 

4. Gallegos DA, Minto MS, Liu F, Hazlett MF, Aryana Yousefzadeh S, Bartelt LC, West AE. Cell-type specific transcriptional adaptations of nucleus accumbens interneurons to amphetamine. Mol Psychiatry. 2022 Feb 16:10.1038/s41380-022-01466-1. doi: 10.1038/s41380-022-01466-1.

5. Nicolas CI, Bronson K, Pendse SN, Efremenko A, Fitzpatrick JM, Minto MS, Mansouri K, Yoon M, Phillips MB, Clewell RA, Andersen ME, Clewell HJ, & McMullen PD (2020). The TTC Data Mart: An interactive browser for threshold of toxicological concern calculations. Computational Toxicology, 15. 

Omics Experience

Tech Stack

AWS

Docker

R

Python

RNA-seq

ATAC-seq

ChIP-seq

CUTnRUN-seq

DNA Methylation

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